Transforming the future of bone healing with innovative solutions.
Understanding the critical issues in current bone repair methods
Bone fractures are very common traumas. Today, 10% of bone defects don't repair, and it can reach 45% for risk patients (diabetes, elderly, osteoporosis, smokers).
In the case of severe trauma, the standard solution is autograft but the amount of available bone is limited, and the surgical procedure is painful for the patient.
Defects don't repair
Risk patients
Advanced 3D bioactive implants that revolutionize bone self-repair
APIOS develops 3D bioactive implants to stimulate bone self-repair. The implant is a scaffold made by 3D printing, which allows control size, shape, and porosity. It can be custom-made for the patient.
Internal and external surfaces are coated with a biomimetic film containing an osteo-inductive protein (BMP-2), which activates bone repair. The 3D bioactive implant is ready-to-use for the surgeon, which simplify the surgical procedure.
Scaffold structure promotes bone growth
BMP-2 protein coating activates bone repair
3D printed to match patient needs
Simplified surgical procedure
Discover how our technology is transforming various medical procedures
Latest news
We are very happy to have been selected by CNRS Innovation to PITCH our APIOS project at Biolabs Investor Day, the 11st of March 2025 in Paris. See you there!
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We were proud to participate to Tech & Fest 2025 on CNRS space. Thank you for the discussions.
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We are proud to have received a visit from Thierry Lhermitte, ambassador of the Medical Research Fondation, to present him our APIOS technology.
Read full article about Read more about A visit from Thierry LhermitteExplore our scientific publications, patents, and media coverage
3D-Printed Osteoinductive Polymeric Scaffolds with Optimized Architecture to Repair a Sheep Metatarsal Critical-Size Bone Defect.
DOI: 10.1002/adhm.202301692Additive Manufacturing of Material Scaffolds for Bone Regeneration: Toward Application in the Clinics.
DOI: 10.1002/adfm.2020069673D-printed scaffold combined to 2D osteoinductive coatings to repair a critical-size mandibular bone defect.
DOI: 10.1016/j.mtbio.2021.100113Surface delivery of tunable doses of BMP-2 from an adaptable polymeric scaffold induces volumetric bone regeneration.
DOI: 10.1016/j.biomaterials.2016.06.001Implantable medical device for bone repair.
WO2022063771A1Process for preparing a surface coated by crosslinked polyelectrolyte multilayer films as a biomimetic reservoir for proteins.
WO2010081884A2Meet our dedicated team of experts working to revolutionize bone repair technology
Founding Director of a Research Ireland Centre for Research in Medical Devices (CÚRAM)
Honorary Dean at Faculty of Dental Surgery of Strasbourg
Dental surgeon
Expert in Dental Implantology
